الگوی تغییرات سنی اولین سکته قلبی حاد در رفسنجان، طی سال‌های 1382 تا 1391: آیا سن کاهش یافته؟

Background and Objective: Age increase is known as a risk factor for cardiovascular disease and acute&nbsp; myocardial infarction (AMI), but younger women and men are also at risk. The aim of this study was to evaluate the age changes of first AMI and risk factors affecting the patients admitted to the cardiac care unit of Ali- ibn- Abi Talib&nbsp; hospital in Rafsanjan during the years 2003 to 2012. Materials and Methods: This cross-sectional study was conducted on 1247 records of patients with first AMI hospitalized during the years 2003 to 2012. The variables examined in this study included age, gender, smoking, family history of MI , history of diabetes, systolic and diastolic blood pressure, triglycerides, HDL (High-density lipoprotein), LDL (Low-density lipoprotein) and total cholesterol of blood levels as independent variables and age of first AMI as the dependent variable. Data were analyzed using independent two-sample t- test and multiple linear regression. Results: The average age of first AMI in these patients was 60.54&plusmn;14.00 years. During the years examined, the age of first AMI was significantly increased to 9 years (p= 0.001). Based on multiple linear regression model, the male sex (B= -3.48, p=0.003), smoking history (B= -5.10, P<0.001), positive family history (B=-5.13, p<0.001), and high blood triglyceride levels (B=-3.52, P<0.001) had significant effect on decreasing the age of first AMI. Conclusion: Despite increasing the mean of age process of AMI in this study, screening people at high risk including men, people with smoking history, positive family history and hyperlipidemia in terms of prognostic factors of this disease can be useful in controlling its incidence among young people. Key words: Myocardial infarction, Age, Risk factors, Rafsanjan Funding: This research was funded by Tehran University of Medical Sciences. Conflict of interest: None declared. Ethical approval: The Ethics Committee of Tehran University of Medical Sciences approved the study. How to cite this article: Kamiab Z, Mirzaei M, Dabiran S. The Pattern of Age Changes of First Acute Myocardial Infarction in Rafsanjan During 2003 to 2012: Has Age Decreased?. J Rafsanjan Univ Med Sci 2017; 15(10): 1015-26. [Farsi]